Automated description from the Alliance of Genome Resources (Release 7.0.0)
Enables extracellularly ATP-gated monoatomic cation channel activity. Acts upstream of or within several processes, including excitatory postsynaptic potential; nitric oxide biosynthetic process; and vasodilation. Located in apical part of cell. Is active in lysosomal membrane. Is expressed in several structures, including cardiovascular system; gut; immune system; nervous system; and viscerocranium. Orthologous to human P2RX4 (purinergic receptor P2X 4).