Automated description from the Alliance of Genome Resources (Release 7.0.0)
Enables transcription coregulator activity. Involved in negative regulation of transcription by RNA polymerase II. Acts upstream of or within regulation of DNA-templated transcription. Located in nucleus. Part of ESC/E(Z) complex. Is expressed in several structures, including autopod; brain ventricular layer; early conceptus; genitourinary system; and gut. Used to study Hirschsprung's disease and Waardenburg syndrome. Orthologous to human AEBP2 (AE binding protein 2).