Automated description from the Alliance of Genome Resources (Release 7.0.0)
Enables ubiquitin ligase-substrate adaptor activity. Involved in ubiquitin-dependent protein catabolic process via the C-end degron rule pathway. Acts upstream of or within branching involved in prostate gland morphogenesis; epithelial cell maturation involved in prostate gland development; and protein ubiquitination. Located in cytoplasm and nucleus. Is expressed in several structures, including central nervous system; genitourinary system; liver; retina; and spleen. Used to study type 2 diabetes mellitus. Orthologous to human FEM1B (fem-1 homolog B).