Automated description from the Alliance of Genome Resources (Release 7.0.0)
Enables disordered domain specific binding activity. Involved in clathrin-dependent endocytosis and postsynaptic neurotransmitter receptor internalization. Located in mitochondrion. Part of AP-2 adaptor complex. Is active in glutamatergic synapse. Is expressed in several structures, including alimentary system; genitourinary system; nervous system; respiratory system; and sensory organ. Human ortholog(s) of this gene implicated in autosomal dominant intellectual developmental disorder. Orthologous to human AP2M1 (adaptor related protein complex 2 subunit mu 1).