Automated description from the Alliance of Genome Resources (Release 7.0.0)
Predicted to enable ATP hydrolysis activity and ubiquitin protein ligase activity. Involved in angiogenesis; defense response to bacterium; and lipid ubiquitination. Predicted to be located in cytoplasm and lipid droplet. Predicted to be active in cytosol and nucleolus. Is expressed in genitourinary system; gut; heart; and pericardial component. Human ortholog(s) of this gene implicated in Moyamoya disease. Orthologous to human RNF213 (ring finger protein 213).