Automated description from the Alliance of Genome Resources (Release 5.4.0)
Predicted to enable structural molecule activity. Involved in negative regulation of gene expression; positive regulation of gene expression; and tight junction assembly. Located in bicellular tight junction and plasma membrane. Is expressed in several structures, including alimentary system; cardiovascular system; central nervous system; genitourinary system; and submandibular gland primordium. Human ortholog(s) of this gene implicated in schizophrenia. Orthologous to human CLDN5 (claudin 5).