Go Annotations as Summary Text (Tabular View) (GO Graph)

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Automated description from the Alliance of Genome Resources (Release 8.3.0)

Enables RNA polymerase II cis-regulatory region sequence-specific DNA binding activity; chromatin DNA binding activity; and lncRNA binding activity. Contributes to promoter-specific chromatin binding activity. Involved in facultative heterochromatin formation and negative regulation of transcription by RNA polymerase II. Acts upstream of or within several processes, including oligodendrocyte differentiation; positive regulation of cell population proliferation; and random inactivation of X chromosome. Located in nucleus and sex chromatin. Part of nucleus; protein-DNA complex; and ribonucleoprotein complex. Is expressed in several structures, including bone; branchial arch; central nervous system; limb bud; and sensory organ. Human ortholog(s) of this gene implicated in renal Wilms' tumor. Orthologous to human SUZ12 (SUZ12 polycomb repressive complex 2 subunit).

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Gene Ontology Evidence Code Abbreviations:

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