Automated description from the Alliance of Genome Resources (Release 7.0.0)
Predicted to enable DNA-binding transcription repressor activity, RNA polymerase II-specific; RNA polymerase II cis-regulatory region sequence-specific DNA binding activity; and chromatin binding activity. Acts upstream of or within several processes, including enteroendocrine cell differentiation; neurogenesis; and regulation of oligodendrocyte differentiation. Located in nucleus. Is expressed in several structures, including central nervous system; future brain; and gut. Orthologous to human NKX6-1 (NK6 homeobox 1).