Automated description from the Alliance of Genome Resources (Release 7.0.0)
Enables endopeptidase activity. Involved in several processes, including cellular response to lipopolysaccharide; positive regulation of tumor necrosis factor production; and positive regulation of tumor necrosis factor-mediated signaling pathway. Located in extracellular space. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; immune system; and limb. Human ortholog(s) of this gene implicated in breast cancer and carotid artery disease. Orthologous to human MMP8 (matrix metallopeptidase 8).