Automated description from the Alliance of Genome Resources (Release 7.1.0)
Enables protein homodimerization activity. Involved in several processes, including growth plate cartilage chondrocyte proliferation; negative regulation of mesoderm development; and negative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway. Acts upstream of or within several processes, including cellular response to cadmium ion; negative regulation of BMP signaling pathway; and signal transduction involved in regulation of gene expression. Located in extracellular space. Is expressed in several structures, including alimentary system; blastocyst; brain; genitourinary system; and paraxial mesenchyme. Orthologous to human CER1 (cerberus 1, DAN family BMP antagonist).