Automated description from the Alliance of Genome Resources (Release 7.0.0)
Enables several functions, including DNA-binding transcription factor binding activity; histone H3 demethylase activity; and transcription coregulator activity. Involved in several processes, including positive regulation of cell population proliferation; regulation of myeloid cell differentiation; and regulation of transcription by RNA polymerase II. Acts upstream of or within DNA repair-dependent chromatin remodeling; negative regulation of neurogenesis; and nervous system development. Located in nucleus. Part of chromatin. Is expressed in several structures, including articular cartilage; brain; reproductive system; retina; and urinary system. Orthologous to human KDM1A (lysine demethylase 1A).