Automated description from the Alliance of Genome Resources (Release 7.1.0)
Enables serine-type endopeptidase activity. Involved in exocytosis. Acts upstream of or within zymogen activation. Located in several cellular components, including dendrite; synaptic cleft; and terminal bouton. Is active in Schaffer collateral - CA1 synapse; glutamatergic synapse; and presynapse. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; immune system; and sensory organ. Human ortholog(s) of this gene implicated in autosomal recessive intellectual developmental disorder 1 and intellectual disability. Orthologous to human PRSS12 (serine protease 12).