Automated description from the Alliance of Genome Resources (Release 5.4.0)
Enables identical protein binding activity and tumor necrosis factor receptor superfamily binding activity. Involved in several processes, including intracellular signal transduction; positive regulation of secretion by cell; and regulation of DNA-templated transcription. Acts upstream of or within several processes, including cellular response to cytokine stimulus; mammary gland development; and positive regulation of intracellular signal transduction. Predicted to be located in cytoplasm; extracellular space; and plasma membrane. Is expressed in genitourinary system; hemolymphoid system; and hindlimb long bone. Used to study autosomal recessive osteopetrosis 2 and osteoporosis. Human ortholog(s) of this gene implicated in autosomal recessive osteopetrosis 2 and osteoporosis. Orthologous to human TNFSF11 (TNF superfamily member 11).