Automated description from the Alliance of Genome Resources (Release 7.1.0)
Enables phosphatidylinositol 3-kinase regulatory subunit binding activity and protein heterodimerization activity. Involved in several processes, including insulin receptor signaling pathway; intracellular glucose homeostasis; and positive regulation of protein import into nucleus. Acts upstream of or within positive regulation of cell adhesion; regulation of actin filament organization; and regulation of protein localization to plasma membrane. Located in focal adhesion and nucleus. Is expressed in several structures, including early embryo; genitourinary system; liver; musculature; and spleen. Human ortholog(s) of this gene implicated in pancreatic ductal adenocarcinoma. Orthologous to human PIK3R2 (phosphoinositide-3-kinase regulatory subunit 2).