Automated description from the Alliance of Genome Resources (Release 7.0.0)
Enables 5-methylcytosine dioxygenase activity. Involved in several processes, including dendrite morphogenesis; inner cell mass cell differentiation; and positive regulation of transcription by RNA polymerase II. Acts upstream of or within DNA demethylation and epigenetic programing of male pronucleus. Located in nucleus. Is expressed in several structures, including brain; early conceptus; immune system; lower urogenital tract; and reproductive system. Orthologous to human TET1 (tet methylcytosine dioxygenase 1).