Automated description from the Alliance of Genome Resources (Release 7.1.0)
Enables kinetochore binding activity and protein kinase binding activity. Involved in several processes, including attachment of spindle microtubules to kinetochore; establishment of protein localization; and regulation of chromosome segregation. Acts upstream of or within regulation of protein stability and spindle assembly involved in female meiosis I. Located in kinetochore. Part of outer kinetochore. Is expressed in dentate gyrus subgranular zone; testis; and thymus. Human ortholog(s) of this gene implicated in primary autosomal recessive microcephaly 13. Orthologous to human CENPE (centromere protein E).