Automated description from the Alliance of Genome Resources (Release 7.0.0)
Predicted to enable DNA/RNA hybrid binding activity; chromatin binding activity; and zinc ion binding activity. Predicted to contribute to RNA polymerase I activity. Predicted to be involved in negative regulation of protein localization to nucleolus and rRNA transcription. Located in chromosome and nucleus. Part of RNA polymerase I complex. Is expressed in several structures, including alimentary system; brain; early conceptus; genitourinary system; and integumental system. Human ortholog(s) of this gene implicated in acrofacial dysostosis Cincinnati type. Orthologous to human POLR1A (RNA polymerase I subunit A).