Automated description from the Alliance of Genome Resources (Release 7.0.0)
Enables ketohexokinase activity. Involved in fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate. Acts upstream of or within fructose metabolic process and regulation of glycogen metabolic process. Located in cytoplasm and nucleus. Is active in cytosol. Is expressed in alimentary system; central nervous system; liver; and retina. Human ortholog(s) of this gene implicated in essential fructosuria. Orthologous to human KHK (ketohexokinase).