Automated description from the Alliance of Genome Resources (Release 7.0.0)
Enables cysteine-type peptidase activity; peptidase activator activity involved in apoptotic process; and serine-type endopeptidase activity. Involved in T cell mediated cytotoxicity and proteolysis. Acts upstream of or within negative regulation of myelination; positive regulation of apoptotic signaling pathway; and positive regulation of microglial cell activation. Located in cytoplasm. Is expressed in several structures, including alimentary system; central nervous system; eye; genitourinary system; and immune system. Used to study schizophrenia. Human ortholog(s) of this gene implicated in Papillon-Lefevre disease and aggressive periodontitis. Orthologous to human CTSC (cathepsin C).