Automated description from the Alliance of Genome Resources (Release 7.1.0)
Enables RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in natural killer cell differentiation; negative regulation of DNA-templated transcription; and positive regulation of DNA-templated transcription. Acts upstream of or within cellular response to interleukin-4 and positive regulation of gene expression. Predicted to be part of RNA polymerase II transcription regulator complex. Predicted to be active in nucleus. Is expressed in several structures, including adipose tissue; alimentary system; brain; genitourinary system; and heart. Used to study inflammatory bowel disease. Orthologous to human NFIL3 (nuclear factor, interleukin 3 regulated).