Automated description from the Alliance of Genome Resources (Release 5.4.0)
Predicted to enable several functions, including nuclear localization sequence binding activity; promoter-specific chromatin binding activity; and transcription coactivator activity. Predicted to be a structural constituent of nuclear pore. Predicted to be involved in several processes, including nucleocytoplasmic transport; positive regulation of mRNA splicing, via spliceosome; and post-transcriptional tethering of RNA polymerase II gene DNA at nuclear periphery. Predicted to act upstream of or within mRNA transport; protein transport; and proteolysis. Located in nucleus. Is expressed in several structures, including nervous system and neural retina. Human ortholog(s) of this gene implicated in T-cell acute lymphoblastic leukemia. Orthologous to human NUP98 (nucleoporin 98 and 96 precursor).