Automated description from the Alliance of Genome Resources (Release 7.1.0)
Enables mitogen-activated protein kinase binding activity. Involved in negative regulation of osteoblast differentiation; regulation of bone mineralization; and regulation of stress-activated MAPK cascade. Located in late endosome; mitochondrial intermembrane space; and phagophore assembly site. Colocalizes with autophagosome. Is expressed in several structures, including central nervous system; genitourinary system; gut; hemolymphoid system; and liver and biliary system. Orthologous to human NBR1 (NBR1 autophagy cargo receptor).