Go Annotations as Summary Text (Tabular View) (GO Graph)

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Automated description from the Alliance of Genome Resources (Release 8.3.0)

Predicted to enable RNA polymerase II-specific DNA-binding transcription factor binding activity; histone deacetylase binding activity; and transcription coregulator activity. Involved in positive regulation of transcription by RNA polymerase II. Acts upstream of or within negative regulation of DNA-templated transcription and response to type II interferon. Predicted to be located in PML body; cell surface; and cytosol. Is expressed in bladder; central nervous system; and retina. Used to study MHC class II deficiency and osteoporosis. Human ortholog(s) of this gene implicated in several diseases, including Addison's disease; MHC class II deficiency; multiple sclerosis; rheumatoid arthritis (multiple); and systemic lupus erythematosus. Orthologous to human CIITA (class II major histocompatibility complex transactivator).

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Gene Ontology Evidence Code Abbreviations:

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