Automated description from the Alliance of Genome Resources (Release 7.0.0)
Predicted to enable enzyme binding activity and ubiquitin-protein transferase activity. Involved in negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator. Acts upstream of or within heart development; positive regulation of cell population proliferation; and regulation of heart rate. Predicted to be located in nucleoplasm. Predicted to be part of transcription repressor complex. Is expressed in several structures, including eye; genitourinary system; liver; lung; and spleen. Used to study dilated cardiomyopathy. Orthologous to human MDM4 (MDM4 regulator of p53).