Automated description from the Alliance of Genome Resources (Release 7.1.0)
Enables protein serine/threonine kinase activity. Involved in several processes, including negative regulation of nitric oxide biosynthetic process; regulation of gene expression; and regulation of signal transduction. Acts upstream of or within extrinsic apoptotic signaling pathway via death domain receptors; nervous system development; and positive regulation of centrosome duplication. Located in spindle pole centrosome. Is active in several cellular components, including Schaffer collateral - CA1 synapse; glutamatergic synapse; and postsynaptic density. Is expressed in several structures, including central nervous system; genitourinary system; heart; musculature; and somite. Orthologous to human ROCK2 (Rho associated coiled-coil containing protein kinase 2).