Go Annotations as Summary Text (Tabular View) (GO Graph)

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Automated description from the Alliance of Genome Resources (Release 9.0.0)

Predicted to enable growth factor activity; protein homodimerization activity; and signaling receptor binding activity. Involved in several processes, including nephron epithelium morphogenesis; nervous system development; and positive regulation of morphogenesis of an epithelium. Acts upstream of or within several processes, including kidney development; organ induction; and peristalsis. Predicted to be located in Golgi apparatus. Predicted to be part of signaling receptor complex. Predicted to be active in extracellular region. Is expressed in several structures, including alimentary system; central nervous system; embryo mesenchyme; genitourinary system; and immune system. Used to study Hirschsprung's disease. Human ortholog(s) of this gene implicated in several diseases, including Hirschsprung's disease; Parkinsonism; anxiety disorder; depressive disorder; and heroin dependence. Orthologous to human GDNF (glial cell derived neurotrophic factor).

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Gene Ontology Evidence Code Abbreviations:

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