Automated description from the Alliance of Genome Resources (Release 7.0.0)
Enables BMP binding activity; BMP receptor activity; and transforming growth factor beta receptor activity, type I. Involved in several processes, including BMP signaling pathway; ovarian cumulus expansion; and skeletal system development. Acts upstream of or within several processes, including cartilage condensation; neuron differentiation; and positive regulation of extrinsic apoptotic signaling pathway via death domain receptors. Located in plasma membrane. Is expressed in several structures, including alimentary system; central nervous system; embryo mesenchyme; limb; and sensory organ. Human ortholog(s) of this gene implicated in acromesomelic dysplasia-3; brachydactyly type A1D; brachydactyly type A2; and osteochondrodysplasia. Orthologous to human BMPR1B (bone morphogenetic protein receptor type 1B).