Automated description from the Alliance of Genome Resources (Release 7.1.0)
Enables DNA binding activity and DNA-binding transcription repressor activity, RNA polymerase II-specific. Acts upstream of or within several processes, including hemopoiesis; negative regulation of macromolecule biosynthetic process; and regulation of lymphocyte activation. Located in nucleus. Is expressed in several structures, including alimentary system; brain; genitourinary system; immune system; and integumental system. Human ortholog(s) of this gene implicated in B-cell lymphoma and diffuse large B-cell lymphoma. Orthologous to human BCL6 (BCL6 transcription repressor).