Automated description from the Alliance of Genome Resources (Release 7.0.0)
Predicted to enable estradiol 17-beta-dehydrogenase [NAD(P)] activity; testosterone 17-beta-dehydrogenase (NADP+) activity; and testosterone dehydrogenase (NAD+) activity. Predicted to be involved in steroid biosynthetic process. Predicted to act upstream of or within lipid metabolic process. Predicted to be active in endoplasmic reticulum. Is expressed in ovary and testis. Used to study 17-beta hydroxysteroid dehydrogenase 3 deficiency. Human ortholog(s) of this gene implicated in 17-beta hydroxysteroid dehydrogenase 3 deficiency and disorder of sexual development. Orthologous to human HSD17B3 (hydroxysteroid 17-beta dehydrogenase 3).