Automated description from the Alliance of Genome Resources (Release 7.1.0)
Enables oxysterol binding activity and voltage-gated monoatomic anion channel activity. Involved in negative regulation of reactive oxygen species metabolic process and regulation of mitophagy. Acts upstream of or within behavioral fear response; learning; and neuron-neuron synaptic transmission. Located in membrane and mitochondrion. Is expressed in several structures, including central nervous system; eye; liver; placenta; and testis. Human ortholog(s) of this gene implicated in prostate cancer. Orthologous to human VDAC1 (voltage dependent anion channel 1).