Automated description from the Alliance of Genome Resources (Release 7.1.0)
Enables serine-type endopeptidase inhibitor activity. Acts upstream of or within several processes, including negative regulation of nitric oxide mediated signal transduction; regulation of calcium ion transport; and sperm capacitation. Located in extracellular space. Is expressed in several structures, including embryo ectoderm; genitourinary system; gut; liver; and yolk sac. Human ortholog(s) of this gene implicated in pancreatitis. Orthologous to human SPINK1 (serine peptidase inhibitor Kazal type 1).