Automated description from the Alliance of Genome Resources (Release 7.0.0)
Predicted to enable ATP binding activity and DNA binding activity. Involved in regulation of chromatin organization. Acts upstream of or within several processes, including cholangiocyte proliferation; hepatocyte proliferation; and stem cell proliferation. Located in chromosome; cytoplasm; and nucleolus. Is expressed in several structures, including alimentary system; brain; genitourinary system; sensory organ; and skin. Human ortholog(s) of this gene implicated in several diseases, including Crohn's disease; colorectal cancer; endocrine gland cancer (multiple); graft-versus-host disease; and human immunodeficiency virus infectious disease. Orthologous to human MKI67 (marker of proliferation Ki-67).