Automated description from the Alliance of Genome Resources (Release 6.0.0)
Predicted to enable metalloendopeptidase activity. Predicted to be involved in proteolysis. Located in plasma membrane. Is expressed in foregut; nasal cavity epithelium; respiratory system; and thymus. Human ortholog(s) of this gene implicated in breast cancer; estrogen-receptor positive breast cancer; invasive ductal carcinoma; lung adenocarcinoma; and lung non-small cell carcinoma. Orthologous to human ADAM28 (ADAM metallopeptidase domain 28).