Automated description from the Alliance of Genome Resources (Release 8.3.0)
A structural constituent of ribosome. Predicted to be involved in several processes, including cytoplasmic translation; embryonic brain development; and negative regulation of transcription by RNA polymerase II. Located in cytoplasm. Part of cytosolic large ribosomal subunit. Is active in synapse. Colocalizes with smooth endoplasmic reticulum. Is expressed in several structures, including limb; nervous system; otocyst; skin; and surface ectoderm. Human ortholog(s) of this gene implicated in autistic disorder and syndromic X-linked mental retardation 35. Orthologous to human RPL10 (ribosomal protein L10).
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