Automated description from the Alliance of Genome Resources (Release 7.0.0)
Enables 17-beta-hydroxysteroid dehydrogenase (NADP+) activity; estradiol 17-beta-dehydrogenase [NAD(P)] activity; and testosterone dehydrogenase [NAD(P)] activity. Involved in estrogen biosynthetic process and testosterone biosynthetic process. Acts upstream of or within several processes, including adipose tissue development; lysosome organization; and skeletal muscle tissue development. Predicted to be located in cytoplasm. Predicted to be active in cytosol. Is expressed in several structures, including adrenal gland; genitourinary system; spleen; submandibular gland; and trachea. Orthologous to human HSD17B1 (hydroxysteroid 17-beta dehydrogenase 1).