Automated description from the Alliance of Genome Resources (Release 7.0.0)
Predicted to enable ephrin receptor activity. Involved in angiogenesis; ephrin receptor signaling pathway; and heart morphogenesis. Acts upstream of or within positive regulation of T cell costimulation; positive regulation of aorta morphogenesis; and venous blood vessel morphogenesis. Predicted to be located in plasma membrane. Predicted to be part of receptor complex. Is expressed in several structures, including alimentary system; brain; cardiovascular system; genitourinary system; and sensory organ. Used to study cystic kidney disease. Human ortholog(s) of this gene implicated in central conducting lymphatic anomaly. Orthologous to human EPHB4 (EPH receptor B4).