Automated description from the Alliance of Genome Resources (Release 7.0.0)
Enables several functions, including PDZ domain binding activity; transforming growth factor beta binding activity; and transforming growth factor beta receptor activity. Involved in several processes, including definitive erythrocyte differentiation; heart development; and positive regulation of SMAD protein signal transduction. Acts upstream of or within several processes, including negative regulation of apoptotic process involved in morphogenesis; positive regulation of transmembrane receptor protein serine/threonine kinase signaling pathway; and vasculogenesis. Located in cell surface and endoplasmic reticulum. Is expressed in several structures, including brain; early conceptus; heart; jaw; and ovary. Orthologous to human TGFBR3 (transforming growth factor beta receptor 3).