Go Annotations as Summary Text (Tabular View) (GO Graph)

---

Automated description from the Alliance of Genome Resources (Release 8.3.0)

Enables microtubule binding activity and protein homodimerization activity. Involved in cytoskeleton organization. Acts upstream of or within several processes, including cytoplasmic microtubule organization; regulation of microtubule polymerization or depolymerization; and retrograde axonal transport. Located in several cellular components, including H zone; cytoskeleton; and endoplasmic reticulum. Is active in Z disc and type III intermediate filament. Is expressed in several structures, including alimentary system; genitourinary system; integumental system; musculature; and nervous system. Used to study hereditary sensory and autonomic neuropathy type 6 and hereditary sensory neuropathy. Human ortholog(s) of this gene implicated in epidermolysis bullosa simplex and hereditary sensory and autonomic neuropathy type 6. Orthologous to human DST (dystonin).

---

---

---

Gene Ontology Evidence Code Abbreviations:

---