Automated description from the Alliance of Genome Resources (Release 9.0.0)
Predicted to enable prostaglandin E receptor activity. Involved in several processes, including cellular response to mechanical stimulus; regulation of cytokine production; and regulation of stress fiber assembly. Acts upstream of or within several processes, including regulation of ossification; response to lipopolysaccharide; and response to nematode. Predicted to be located in neuron projection terminus; neuronal cell body; and nuclear membrane. Predicted to be active in plasma membrane. Is expressed in several structures, including 8-cell stage conceptus; arterial system; central nervous system; genitourinary system; and skin. Used to study dilated cardiomyopathy. Human ortholog(s) of this gene implicated in ankylosing spondylitis; arteriosclerosis; aspirin-induced respiratory disease; and ulcerative colitis. Orthologous to human PTGER4 (prostaglandin E receptor 4).
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