Automated description from the Alliance of Genome Resources (Release 6.0.0)
Enables several functions, including guanyl-nucleotide exchange factor activity; microtubule binding activity; and signaling receptor binding activity. Involved in several processes, including brain-derived neurotrophic factor receptor signaling pathway; positive regulation of neuron projection development; and regulation of dopaminergic neuron differentiation. Acts upstream of or within ephrin receptor signaling pathway; positive regulation of axonogenesis; and small GTPase mediated signal transduction. Located in kinocilium; pericentriolar material; and plasma membrane. Is expressed in several structures, including embryo ectoderm; genitourinary system; sensory organ; skin; and tooth. Human ortholog(s) of this gene implicated in neurodevelopmental disorder with language delay and seizures. Orthologous to human TIAM1 (TIAM Rac1 associated GEF 1).