Automated description from the Alliance of Genome Resources (Release 7.1.0)
Enables insulin receptor binding activity and signaling receptor complex adaptor activity. Involved in negative regulation of glucose import; negative regulation of signal transduction; and positive regulation of cold-induced thermogenesis. Acts upstream of or within with a negative effect on ERK1 and ERK2 cascade and gene expression. Acts upstream of or within insulin-like growth factor receptor signaling pathway and vascular associated smooth muscle cell migration. Predicted to be located in cytosol. Predicted to be part of protein-containing complex. Is expressed in several structures, including brain; extraembryonic component; genitourinary system; musculoskeletal system; and sensory organ. Orthologous to human GRB10 (growth factor receptor bound protein 10).