Automated description from the Alliance of Genome Resources (Release 7.1.0)
Predicted to enable several functions, including RNA polymerase II cis-regulatory region sequence-specific DNA binding activity; identical protein binding activity; and ubiquitin-like protein ligase binding activity. Involved in negative regulation of type I interferon-mediated signaling pathway and type I interferon-mediated signaling pathway. Located in cytoplasm and nucleus. Is expressed in several structures, including central nervous system; early conceptus; and genitourinary system. Used to study Zika fever. Human ortholog(s) of this gene implicated in Zika fever; immunodeficiency 44; and neutropenia. Orthologous to human STAT2 (signal transducer and activator of transcription 2).