Automated description from the Alliance of Genome Resources (Release 7.0.0)
Predicted to enable RIG-I binding activity; transcription coactivator activity; and ubiquitin protein ligase activity. Involved in defense response to symbiont; negative regulation of viral entry into host cell; and regulation of protein localization. Acts upstream of or within cellular response to leukemia inhibitory factor. Located in cytoplasm and nucleus. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; respiratory system; and sensory organ. Orthologous to human TRIM25 (tripartite motif containing 25).