Automated description from the Alliance of Genome Resources (Release 7.0.0)
Contributes to laminin binding activity. Acts upstream of or within blood vessel morphogenesis; cell adhesion; and cell migration. Located in several cellular components, including muscle tendon junction; neuromuscular junction; and sarcolemma. Part of integrin alpha7-beta1 complex. Is expressed in several structures, including alimentary system; heart; metanephros; nervous system; and skeletal musculature. Used to study congenital muscular dystrophy due to integrin alpha-7 deficiency. Human ortholog(s) of this gene implicated in Duchenne muscular dystrophy; congenital muscular dystrophy due to integrin alpha-7 deficiency; and muscular disease. Orthologous to human ITGA7 (integrin subunit alpha 7).