Automated description from the Alliance of Genome Resources (Release 7.0.0)
Enables several functions, including DNA binding activity; DNA-binding transcription activator activity, RNA polymerase II-specific; and lysine-acetylated histone binding activity. Involved in several processes, including blastocyst development; regulation of asymmetric cell division; and regulation of gene expression. Acts upstream of or within several processes, including blastocyst development; cell fate commitment involved in formation of primary germ layer; and regulation of DNA-templated transcription. Located in cytoplasm and nucleus. Part of chromatin and transcription repressor complex. Is expressed in several structures, including alimentary system; central nervous system; early conceptus; gonad; and mesoderm. Human ortholog(s) of this gene implicated in embryonal carcinoma and seminoma. Orthologous to human POU5F1 (POU class 5 homeobox 1) and POU5F1B (POU class 5 homeobox 1B).