Automated description from the Alliance of Genome Resources (Release 7.1.0)
Enables DNA binding activity and DNA-binding transcription repressor activity, RNA polymerase II-specific. Involved in several processes, including negative regulation of myoblast differentiation; positive regulation of skeletal muscle tissue regeneration; and regulation of gene expression. Acts upstream of or within several processes, including keratinocyte migration; keratinocyte proliferation; and positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction. Located in nucleus. Part of chromatin. Is expressed in several structures, including brain; early conceptus; genitourinary system; gut; and sensory organ. Used to study type 2 diabetes mellitus. Human ortholog(s) of this gene implicated in type 2 diabetes mellitus. Orthologous to human PPARD (peroxisome proliferator activated receptor delta).