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Glossary Term
Glossary Term Dominant
Definition One of a series of terms applied to the phenotypic effect of a particular allele in reference to another allele (usually the standard wild-type allele) with respect to a given trait. An allele "A" is said to be dominant with respect to the allele "a" if the A/A homozygote and the A/a heterozygote are phenotypically identical and different from the a/a homozygote. An example is the Pmp22(Tr) mutation in mouse, which causes a myelination defect associated with a "trembler" phenotype. Pmp22(Tr)/Pmp22(Tr) and Pmp22(Tr)/Pmp22(+) animals are phenotypically identical, displaying the mutant phenotype, while Pmp22(+)/Pmp22(+) animals are wild-type.
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Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
MGI 6.22
The Jackson Laboratory