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Symbol
Name
ID
Vcp
valosin containing protein
MGI:99919
Phenotype annotations related to behavior/neurological
*Aspects of the system are reported to show a normal phenotype.
Darker colors indicate more annotations
Human Phenotypes
Feeding difficulties in infancy
Back pain
Depression
Emotional lability
Atypical behavior
Personality changes
Hip pain
Myalgia
Disease(s) Associated with VCP
Charcot-Marie-Tooth disease type 2Y
frontotemporal dementia and/or amyotrophic lateral sclerosis 6
inclusion body myopathy with early-onset Paget disease of bone with or without frontotemporal dementia 1
inclusion body myositis

Mouse Phenotypes
behavior/neurological phenotype
impaired spatial learning
increased anxiety-related response
fast extinction of fear memory
impaired coordination
decreased grip strength
seizures
tonic-clonic seizures
Availability Mouse Genotype
Vcptm1Itl/Vcptm1Itl
Vcptm1.1Hiok/Vcp+
Vcptm1Itl/Vcp+ *

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/23/2024
MGI 6.23
The Jackson Laboratory