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Symbol
Name
ID
Runx1
runt related transcription factor 1
MGI:99852
Phenotype annotations related to neoplasm
*Aspects of the system are reported to show a normal phenotype.
Darker colors indicate more annotations
Human Phenotypes
Acute myeloid leukemia
Disease(s) Associated with RUNX1
acute myeloid leukemia

Mouse Phenotypes
neoplasm
increased T cell derived lymphoma incidence
increased incidence of tumors by chemical induction
increased metastatic potential
increased lymphoma incidence
Availability Mouse Genotype
Runx1tm1Spe/Runx1+ *
Runx1tm1(RUNX1)Gcg/Runx1tm1(RUNX1)Gcg
Tg(Mx1-cre)1Cgn/0  (conditional)
Runx1tm2Buch/Runx1tm2Buch
Tg(Mx1-cre)1Cgn/?  (conditional)
Runx1tm3Spe/Runx1tm3Spe
Tg(Mx1-cre)1Cgn/0  (conditional)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/16/2024
MGI 6.23
The Jackson Laboratory