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Symbol
Name
ID
Fgf8
fibroblast growth factor 8
MGI:99604
Phenotype annotations related to embryo
Darker colors indicate more annotations

Mouse Phenotypes
abnormal pharyngeal arch artery morphology
abnormal fourth pharyngeal arch artery morphology
absent fourth pharyngeal arch artery
fourth pharyngeal arch artery hypoplasia
abnormal sixth pharyngeal arch artery morphology
absent sixth pharyngeal arch artery
abnormal third pharyngeal arch artery morphology
enlarged third pharyngeal arch artery
third pharyngeal arch artery hypoplasia
abnormal cardiogenic mesoderm morphology
abnormal neural crest cell apoptosis
abnormal cardiac neural crest cell migration
abnormal pharyngeal arch morphology
small first pharyngeal arch
abnormal pharyngeal arch mesenchyme morphology
small pharyngeal arch
pharyngeal arch hypoplasia
abnormal developmental patterning
abnormal ectoderm development
abnormal mesoderm development
abnormal rostral-caudal axis patterning
decreased embryo size
abnormal embryonic epiblast morphology
abnormal splanchnic mesoderm morphology
absent mesoderm
small limb buds
abnormal neural fold formation
abnormal neural tube morphology
abnormal neural crest cell morphology
open neural tube
abnormal rhombomere morphology
abnormal primitive streak morphology
absent primitive node
abnormal somite development
absent somites
abnormal primitive streak elongation
abnormal allantois morphology
abnormal amnion morphology
abnormal chorion morphology
Availability Mouse Genotype
Fgf8tm1.1Jyhl/Fgf8tm1.1Jyhl
Fgf8tm1.2Mrt/Fgf8tm1.2Mrt
Fgf8tm1.4Mrt/Fgf8tm1.4Mrt
Fgf8tm1Jyhl/Fgf8tm1Jyhl
Fgf8tm1.1Mrt/Fgf8tm1.2Mrt
Fgf8tm1.2Mrt/Fgf8tm1.4Mrt
Fgf8tm1Mrc/Fgf8tm3Mrc
Fgf8tm1Moon/Fgf8tm1Moon
Mesp1tm2(cre)Ysa/Mesp1+  (conditional)
En1tm7(cre/ESR1)Alj/0
Fgf8tm1.1Jyhl/Fgf8tm1.3Mrt  (conditional)
Fgf8tm1.2Mrt/Fgf8tm1.3Mrt
Tg(Nes-cre)1Atp/0  (conditional)
Fgf8tm1.3Mrt/Fgf8tm1.4Mrt
Tg(Msx2-cre)5Rem/0  (conditional)
Fgf8tm1.3Mrt/Fgf8tm1.4Mrt
Nkx2-5tm1(cre)Rjs/Nkx2-5+  (conditional)
Fgf8tm1.3Mrt/Fgf8tm2Mrt
Nkx2-5tm1(cre)Rjs/Nkx2-5+  (conditional)
Fgf8tm1Mrc/Fgf8tm1Moon
Tfap2atm1(cre)Moon/Tfap2a+  (conditional)
Fgf8tm1Mrc/Fgf8tm1Moon
Hoxa3tm1(cre)Moon/Hoxa3+  (conditional)
Fgf8tm1Mrc/Fgf8tm2Mrc
Tfap2atm1(cre)Moon/Tfap2a+  (conditional)
Fgf8tm1Mrc/Fgf8tm2Mrc
Hoxa3tm1(cre)Moon/Hoxa3+  (conditional)
Fgf8tm2Moon/Fgf8tm1Mrc
Isl1tm1(cre)Sev/Isl1+  (conditional)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/23/2024
MGI 6.23
The Jackson Laboratory